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in is being closely tracked by public health officials. In December 2025 · Ph.D. · BA.3.2 also spent its first few years “underground” before re-emerging as a potential major variant · Gregory tells TODAY.com. Here's what to know about the BA.3.2 variant · where it's spreading · symptoms and the effectiveness of current vaccines. What Is the New COVID Variant · BA.3.2? BA.3.2 was first identified in November 2024 in South Africa. It's a descendent of BA.3 · an omicron subvariant that emerged in 2022 and briefly co-circulated with BA.1 and BA.2 · the CDC said. Its ancestor BA.3 fizzled out · but never disappeared · says Pekosz. Two years and dozens of mutations later · BA.3.2 emerged. It further branched into two sublineages · BA.3.2.1 and BA.3.2.2. Since 2024 · BA.3.2 has moved slowly and quietly · overshadowed by dominant variants like nimbus and XFG — which all descend from BA.2. Last September · BA.3.2 started taking off. "It was under the radar · replicating · until it started to spread more from person to person · " says Pekosz. BA.3.2 has 70–75 mutations in its spike protein — that’s a lot · says Pekosz — which set it apart from JN.1 and LP.8.1

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in is being closely tracked by public health officials. In December 2025
Ph.D.
BA.3.2 also spent its first few years “underground” before re-emerging as a potential major variant
Learn more
Gregory tells TODAY.com. Here's what to know about the BA.3.2 variant
where it's spreading
symptoms and the effectiveness of current vaccines. What Is the New COVID Variant
BA.3.2? BA.3.2 was first identified in November 2024 in South Africa. It's a descendent of BA.3
an omicron subvariant that emerged in 2022 and briefly co-circulated with BA.1 and BA.2
the CDC said. Its ancestor BA.3 fizzled out
but never disappeared
says Pekosz. Two years and dozens of mutations later
BA.3.2 emerged. It further branched into two sublineages
BA.3.2.1 and BA.3.2.2. Since 2024
BA.3.2 has moved slowly and quietly
overshadowed by dominant variants like nimbus and XFG — which all descend from BA.2. Last September
BA.3.2 started taking off. "It was under the radar
replicating
until it started to spread more from person to person
" says Pekosz. BA.3.2 has 70–75 mutations in its spike protein — that’s a lot
says Pekosz — which set it apart from JN.1 and LP.8.1

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